1. Based on the information provided about the regulation of testosterone secretion, propose a testable hypothesis to explain how trenbolone acetate caused Frank’s testicles to shrink.

If Frank stops injecting trenbolone acetate after 3 months his testicles will enlarge and return to normal size eventually because his testicles will start producing testosterone normally.

2. Propose an experiment to test your hypothesis.

Our hypothesis is that if frank keeps taking trenbolone injections his testicles will continue shrinking. So to test this we will use male brown mice. First, you take 8 brown mice all from the same parents(same litter) and inject 4 of them half a milliliter of trenbolone acetate per week on Wednesday for three months. After two months of injections 4 mice will stop and be monitored for three months to see if their …show more content…
Some advocates of anabolic steroid use report that the testicular atrophy associated with the use of trenbolone acetate can be alleviated if users also inject themselves with human chorionic gonadotropin, a hormone similar in structure to LH and FSH and producing the same biological effects as these two hormones. Explain how this treatment might work.

It will work because it will trick the testicles, the hypothalamus is not sending out GnRH to the pituitary gland thus the pituitary gland is not releasing LH and FSH to tell the testicles to produce testosterone to producing. His testicles will enlarge and return to normal size because they are making testosterone and sperm again.

4. Men who develop testicular cancer usually have the affected testicle surgically removed. Obviously the removal of one testicle reduces blood levels of testosterone. However, over the course of several months, levels of testosterone return to normal. In addition, the size of the remaining testicle typically increases to almost twice its original size. Explain these results in terms of the mechanisms regulating testosterone secretion by the