Hemophilia There are hundreds of different genetic disorders. Hemophilia is a sex- Linked disorder that affects the way a person’s blood clots. A sex-linked disorder has to do with the XX chromosomes of the mother and the XY chromosomes of the father. These genes have more functions than just identifying the sex of the person. Sometimes there are genetic mutations to these genes or certain traits that are passed down from parent to child. When a normal healthy person gets injured there
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Hemophilia & Transposons Hemophilia is an inherited genetic disorder that impairs the body’s ability to coagulate blood or control blood clotting. Hemophiliacs have problems in the blood coagulation mechanism and blood platelets and/or blood vessel defects that cause the individual to have problems forming blood clots to stop bleeding. The individuals tend to bleed for longer periods then normal individuals. Hemophiliacs do not bleed more intensely than normal individuals but due to the
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pregnant. She is excited, but she is worried. Her brother has hemophilia. Hemophilia is a sex-linked, recessive trait. If she carries the gene for hemophilia and she has a girl, what are the chances that the baby will have hemophilia? If she has a boy, what are the chances that the baby will have hemophilia? How would this change if her husband has hemophilia, too? a. Girl baby: b. Boy baby: c. Girl baby (if Dad has hemophilia): d. Boy baby (if Dad has
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she is pregnant. She is excited, but she is worried. Her brother has hemophilia. Hemophilia is a sex-linked, recessive trait. If she carries the gene for hemophilia and she has a girl, what are the chances that the baby will have hemophilia? If she has a boy, what are the chances that the baby will have hemophilia? How would this change if her husband has hemophilia, too? Girl baby: Boy baby: Girl baby (if Dad has hemophilia): Boy baby (if Dad has
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Hemophilia Russell Stoffel March 25, 2013 C. Engel Biol 101-SA01D Abstract Hemophilia is a sex linked inherited bleeding disorder directly linked to the X chromosome, which is responsible for the increased epidemiology in males. Women become carriers and pass it down to male offspring. The person has a decrease or lack of clotting factors in their blood, specifically factors XIII and IX which prevents their blood from clotting properly, causing
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due to them only having a single X chromosome and hemophilia is a recessive x-linked trait. 5. The probability of Marcy and Tom having a child with hemophilia is 12.5%. This is because Marcy has a 50% chance of being a carrier. Marcy’s children in turn have a 50% chance of receiving a copy of the X chromosome. Thus, there is a 25% chance that any of the children would receive a copy of the recessive X allele from Marcy. Tom does not have hemophilia, so we know that the gene on his X chromosome is
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represent principle 3? Jessica, Terry, Florence and Greg 4. Why are none of the males in figure 5.2 shown as carriers of hemophilia? If the male has an X, then he has the disease. A male can’t carry hemophilia due to them Only having a single X chromosome and hemophilia is an X-linked disease. 5. What is the probability that Marcy and Tom will have any child with hemophilia (irrespective of sex)? Show how you calculate this. The total probability would be 12.5%. This is calculated by marcy
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possible for a female carrier to have a daughter who has hemophilia? Explain your answer using terms such as sex-linked inheritance, sex-linked genes, dominant, recessive, and X and Y chromosomes. Sex-linked inheritance is when a gene is located on a sex chromosome, usually a mutated gene that can cause a disorder. The sex chromosomes are X and Y. The combination of two sex chromosomes determines a person’s sex. XX is female and XY is male. Hemophilia is a rare, sex-linked inherited blood clotting disorder
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4. Why are none of the males in figure 5.2 shown as carriers of hemophilia? Males cannot carry hemophilia because it is an X-linked disease and males only have a single X chromosome. If the male has an X, he has the disease. 5. What is the probability that Marcy and Tom will have any child with hemophilia (irrespective of sex)? Show how you calculate this. The probability of Marcy and Tom having a child with hemophilia is 12.5%. This is because Marcy has a 50% chance of being a carrier
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blindness, Duchenne muscular dystrophy and hemophilia. (O’Neil, 2012). In the case of the recessive mutation that causes hemophilia, a female has to be the carrier of the mutated allele, since she has the X chromosomes only. If the female carrier of the disease mates with a male who has hemophilia (XhY), there would be a one-quarter chance that they would produce a female offspring that has hemophilia (XhXh). Males though are more susceptible to inheriting the hemophilia trait if the mother is a carrier,
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