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Host Defense Case

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Case Example: A 10 year old girl was bitten on the leg by a neighborhood dog and received several stitches 5 days ago. This morning she complained of increasing pain, and her mother noticed that the area around the stitches as red and warm to the touch. Her mother brought her to the pediatrician’s office where she is diagnosed with a wound infection and prescribed a 14-day course of an antibiotic she has taken in the past.
1. What is the first line of defense against infection and tissue injury, and why did it fail in this case? (One sentence)
The first line of defense was skin of the 10 year old girl it failed due to it being punctured by the dog’s teeth which require several stitches to repair.
2. How does the second line of host defense …show more content…
This is known an anaphylaxis reaction which can occur within minutes or hours after exposure. Type I IgE-mediated hypersensitivity reaction is mediated by antigen-specific IgE and products of tissue mast cells. Cells carry various antigens on their surface and are expressed on the plasma membranes to certain mast cells. For example platelets have groups of antigens that are found in no other area in the body. These type of sensitivity are directly related to the reactions to the certain affected organs. Environmental antigens bind to the plasma membranes of certain cells and affectively prompting type I reactions. The tissues commonly affected in a type I reactions are gastrointestinal tract, skin, and respiratory tract. In the case study the 10 year old girl experienced wheezing and hives. Wheezing is a direct result is of narrowing of the airways expressing difficulty breathing. This is promoted by antibiotic uses causing the immune system to produce antibodies to attack invaders of a particular allergen as harmful. The hives also known as urticarial seen as red raised itchy skin patches. Most types of these continuous can be relieved by ingesting and antihistamine and stopping of the antibiotic

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