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Lung Cancer Study

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Lung cancer is the primary cause of cancer-related deaths around the world, accounting for one-third of all deaths (Schiller, et al., 2002). Approximately seventy percent of those diagnosed with lung cancer present with advanced or metastatic cancer (Molina, Yang, Cassivi, Schild, & Adjei, 2008). Non-small-cell cancer alone accounts for approximately eighty-five percent of lung cancers throughout the world (Molina et al., 2008). There are many different forms of treatment for non-small-cell lung cancer, but there has not been a single specific treatment to completely eradicate lung cancer. A few forms of treatments for non-small-cell lung cancer that have been studied and applied over the past ten years are: chemotherapy (platinum-doublet …show more content…
They wanted to show that the administration of erlotinib and chemotherapy would increase the progressiveness of the cancer (Cappuzzo, et al., 2010). Seventy to eighty percent of people who received first-line chemotherapy had progression of their cancer, but when they received another cycle of chemotherapy, there was no change in progression. The study included those who completed the four cycles of platinum-based chemotherapy without progression (Cappuzzo, et al., 2010). The participants were assigned erlotinib (150 mg) or placebo of chemotherapy, until the cancer progressed or death occurred. The study occurred between December 2005 and May 2008, were 1949 participants were enrolled in the study to received platinum-based chemotherapy. Once the cycle of chemotherapy had been completed, 428 participants had shown disease progression, 162 participants had died and 89 participants withdrew. After chemotherapy, 889 people had not shown progression and continued through the study, where 437 were given erlotinib and 447 were given a placebo, which was chemotherapy (Cappuzzo, et al., 2010). The administration of erlotinib was more beneficial than that of chemotherapy. The overall survival was longer in erlotinib than in chemotherapy (Cappuzzo, et al.,

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