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Maladaptive Response to Disorders

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Maladaptive Responses to Immune Disorders
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Maladaptive Responses to Immune Disorders
Introduction
This paper evaluates the pathophysiology of two diseases namely Psoriasis and the Human Immuno-Deficiency Virus (HIV). Basically, psoriasis is an autoimmune inflammatory disease which is said to be complex. The disease is mainly common among individuals who are genetically susceptible and is mainly presented by the inflammatory plaques which develop on one’s skin. Apart from genetic susceptibility, psoriasis is also caused when the immune system mistakes viable cells to be external components. In the past few decades, the pathogenesis of this disease was mainly said to be keratinocyte hyperproliferation. Currently, the pathogenesis of the disease also focuses on the dysregulation of one’s immune system. Primarily, the inflammatory plaques appear as silver-white patches. Conversely, the pathogenesis of HIV is basically attributed to by the extensive degradation of one’s immune system. The HIV pathogenic mechanism is prompted by the presence of HIV virus in one’s immune system. The weakening of the immune system culminates in increased susceptibility to various infections (Dann, 2009).
Differences
There are major evident differences between the two maladaptive responses of the given diseases. For instance, the two diseases result in different ramifications upon one’s immune system. While HIV tends to weaken one’s immune system, psoriasis does not do the same. In addition, it is evident that the two maladaptive responses differ simply by evaluating the symptoms of each. Psoriasis is depicted through the skin abnormalities which form (Langley, 2010). On the other hand, HIV is depicted through various symptoms which include tuberculosis and various chronic infections. The diseases also differ in the manner and rate at

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