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Depression And Psychodynamic Research

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Depression caused by serotonin dis-regulation

Depression is the most prevalent psychiatric disorder and according to World Health Organization approximately 350 million people are suffering from it. Depression affects all people regardless of age, race and socioeconomic group. It is the main cause of disability in the world ( ). Depression is different from simple mood change. It alters the way depressed people eat, sleep, feel about themselves and their attitude towards others. Long lasting depression often is a life-threatening disorder that in extreme cases can lead to suicide (Kanner 2012). It has a neurobiological basis and is associated with functional and structural brain abnormalities. In this essay will be discussed and evaluated …show more content…
This theory states that genes are responsible for depression. It also supports the fact that mood disorder, like some other types of illnesses is an inherited and the closer the genetic relationship, the higher are chances to develop mood disorder.. Studies of twins have been effective for researching the role of genetics factors of depression (Ainswoth 2000). McGuffin in 1994 studied the concordance rates of depression in 411 identical twin pairs and according to his research the depressive symptom score was estimated 79 %. That suggest that depression appear to be heritable illness. 68 pairs of monozygotic twins(identical twins - sharing 100% genetic similarity) versus 109 dizygotic twins (non-identical - twins sharing around 50% of their genes). Based on that research MZ twins showed a significant higher concordance rate of 46% versus DZ twins with 20 %. However, this study can be argued because the rate of both identical twins developing depression is not close to 100% therefore depression is not entirely genetic and there are other factors that can have an impact on a person to develop depression. This genetic explanation is quite limited as it does not consider environmental factors such as childhood experiences, traumatic events, etc. Recent research of twins from age 3 to 63 years supports that. According to that the importance of the environmental factors raises with the age and explains the decline of heritability in adults. That leads to a relatively low influence of genetic factor. Research on the genetic causes of clinical depression has attempted to identify one or more specific genes that may lead to the development of a depressive illness. However recently researchers suggests that there is a genetic linkage between depression and specific region on chromosome 3. That means that the depressed siblings in the families in both studies carried many of the same genetic variations in that

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