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The Role of Hormones in Diabetes

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Submitted By slugo1979
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Blood glucose levels vary over the course of periods of food consumption (after a meal) and periods of fasting (between meals). The two major hormones responsible for sustaining homeostasis are: Insulin and glucagon.
Insulin is produced by the pancreas and is released as blood glucose levels rise. Insulin allows blood glucose to enter the cells, where it can be converted in energy (ATP). This action facilitated by insulin cause glucose concentration to fall which inhibits further insulin release.
When glucose levels decrease below the normal levels (between meals or when is used during exercise), a different hormone is secreted by the pancreas: Glucagon which stimulates the breakdown of glycogen (the glucose’s storage form) to glucose which can be used by muscle cells and released into circulation. When levels rise to normal the pancreas ceases secreting glucagon, so that insulin and glucagon can work together keeping homeostatic blood glucose levels.
In some people this mechanism fails causing either diabetes or hypoglycemia. When glucose levels rises after a meal and remains elevated because our body cannot make enough insulin or cannot use property the insulin it makes we are in the presence of diabetes. There are two different forms of diabetes: Type 1 and Type 2. When a person is diagnosed with Type 1 diabetes it means that his/her immune system attacked the cells in the pancreas that makes insulin and disabled them permanently. Diabetes type 2 is caused by poor lifestyle choices. It takes year to develop. First the cells stop responding to the insulin signals. In order to understand it better I’d like to think of insulin as a key that open up the cells’ door so the glucose can come in. When a person becomes insulin resistant is like if the locks were changed so the pancreas keeps making more and more keys (insulin) in order to find the one that open the

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