Free Essay

Clostriduim Difficile

In:

Submitted By jporta35
Words 1494
Pages 6
flu) pandemic. The estimated transmissibility of the current virus is also not far from the norm. Depending on the methodology used, the calculated basic reproduction number (R0; the number of secondary infections produced by a single infected individual) is 1.2-1.6. This number is similar to that seen with seasonal influenza, while comparable estimates of R0 for the 1918, 1957, and 1968 pandemics ranged from 1.4-2.0. The WHO, however, suggests that there may be a much higher secondary attack rate.
■ COMMENTARY

2. 3. 4.

5.

Government Pandemic Influenza Site: http://www.PandemicFlu.gov/ U.S. Government Pandemic Influenza Site: http://www.PandemicFlu.gov/ World Health Organization http://www.who.int/csr/disease/swineflu/en/index.html Human/Swine A/H1N1 Influenza Origins and Evolution (Wiki) http://tree.bio.ed.ac.uk/groups/influenza/ http://www.thelancet.com/H1N1-flu

The recognition that the initial perception of a high mortality rate was apparently spurious has led to some relaxation of concern. This may, however, be premature. While we have completed the usual influenza season in the Northern Hemisphere, the season is just beginning in the southern latitudes. Furthermore, previous pandemics have come in waves, with the second or third wave sometimes being associated with more severe disease than the original portion of the epidemic. While this was not true of the 1968 pandemic, it was true in 1957-1959 and, especially, in 1918. In fact, concern has been raised about the possible recombination of S-OIV with avian influenza, with the potential for significantly enhance virulence in a virus with a high degree of human-to-human transmissibility. ■
References:
1. Newman AP, et al. Human case of swine influenza A (H1N1) triple reassortant virus infection, Wisconsin. Emerg Infect Dis. 2008;14:14702. Shinde V, et al. Triple-reassortment swine influenza A (H1) in humans in the United States, 2005-9. N Engl J Med. 2009;361: May 7. [Epub ahead of print] Novel Swine-Origin Influenza A (H1N1) Virus Investigation Team. Emergence of a novel swine-origin influenza A (H1N1) virus in humans. N Engl J Med. 2009; 361: May 7. [Epub ahead of print] Belshe RB. Implications of the emergence of a novel H1 influenza virus. N Engl J Med. 2009;361: May 7. [Epub ahead of print] Fraser C, et al. Pandemic potential of a strain of influenza A (H1N1): Early findings. Science. 2009 11 May 2009 [Epub ahead of print] Influenza A (H1N1): animal health (09), swine, Canada. http://www.promedmail.org CDC. Hospitalized patients with novel influenza A (H1N1) virus infection --- California, April – May, 20009. May 18, 2008 / 58(Early Release);1-5.

How Should Laboratories Be Testing for C. difficile?
ABSTRACT & COMMENTARY

By Ellen J. Baron, MD, PhD
Professor of Pathology and Medicine, Stanford University; Medical School Director, Clinical Microbiology Laboratory, Stanford University Medical Center
Dr. Baron reports no financial relationships relevant to this field of study.

2.

3.

4.

5.

6. 7.

Internet Resources:
1. Centers for Disease Control; http://www.cdc.gov/h1n1flu/index.htm U.S.

n november 11, 2008, the association for practitioners in Infection Control and Epidemiology (APIC) announced the results of a one-day prevalence survey conducted between May and August of last year.1 Almost 650 hospitals in 47 states, 12.5% of all the hospitals in the United States, sent in their data. According to the results, more than 12 of every 1,000 inpatients were infected with C. difficile. One major shortcoming of the survey was that 94.4% of the positive results were based on an enzyme immunoassay performed by the laboratory. Thus, the point-prevalence survey actually underestimated the depth of the problem by at least 50%! At a recent SHEA meeting, Gelone reported that laboratories overwhelmingly are using enzyme immunoassays (EIAs) for either toxin B or toxins A and B, and often adding a second test for glutamate dehydrogenase (GDH), an enzyme thought to be uniformly present in all C. difficile strains whether they produced toxin or not.2 Although it had been assumed by most microbiologists that the cell culture cytotoxin neutralization test, technically difficult and slow to generate results (requiring at least overnight incubation for a preliminary result), was the most reliable laboratory assay for CDI diagnosis, only 2% of laboratories in the United States still performed that test. Dale Gerding has long advocated a more rigorous assay, the cytotoxic culture, in which the stool is cultivated onto C. difficile selective agar, today’s

O

Infectious Disease Alert

63

best formula being cycloserine-cefoxitin-fructose horse blood taurocholate agar, incubated anaerobically. Organisms phenotypically (and by smell) resembling C. difficile are further incubated in an anaerobic broth at least overnight and sometimes for several days, and the broth is then tested for cytotoxin. This test is slow, but it does yield an isolate that can be typed, for example, as the NAP1 hypervirulent strain currently sweeping across the United States.3 Laboratory and Infection Prevention scientists at Johns Hopkins Hospital recently threw the longstanding reliance on both EIAs and cytotoxin neutralization into question. Their in-house cell culture cytotoxin neutralization test was only 67% sensitive compared to cytotoxic culture assay (the true gold standard).4 A PCR for toxin B gene sequences (tcdB gene) was 83.6% sensitive compared with cytotoxic culture, but increased to 90.9% when the previous “standard” cell culture cytotoxin B assay was used as the comparison, thus highlighting that the sensitivity of a test can vary based on the rigor of the comparative standard. Three years ago, the same Hopkins’ workers published an influential paper advocating a two-step approach using GDH as a preliminary screening test and following a positive GDH result with a confirmatory test, such as cell culture cytotoxin neutralization.5 In that paper, they reported that a popular toxin A and B EIA test, likely the primary assay used to test for CDI in the APIC prevalence study, was only 36% sensitive against cell \culture cytotoxin neutralization.4 The results were delayed because of the need to perform two tests, with batching of the second confirmatory test. That approach was revisited in their 2009 paper, in which a real-time PCR test for a toxin B gene sequence was superior to other methods, with a sensitivity of 86.3%, the most sensitive of all tests compared with the goldstandard cytotoxic culture.4 Sloan et al from Mayo Clinic also suspected that laboratories were missing important cases using the two-step approach.6 They developed an in-house PCR test for a toxin B genetic sequence and evaluated several EIAs and a GDH test, comparing it to the appropriate cytotoxic culture. At best, the sensitivity was 48% among all the EIA assays tested. Contrary to popular belief, the GDH assay also detected only 32% of the toxin-positive C. difficile recovered by culture. Even their home-brew PCR was only 86% sensitive compared with cytotoxic culture. If the point-prevalence study data are reassessed with the assumption that the EIAs used for 94.4% of the testing performed during the survey are failing to detect as many as 52% of the patients with CDI, the prevalence
64

reported in the study could be only half of the true prevalence.
■ COMMENTARY

Clearly the use of more accurate and rapid molecular tools in the laboratory will contribute to the ability to rapidly identify patients who need more aggressive treatment and will facilitate infection control interventions with enhanced potential to be effective. ■
References
1. Jarvis WR, et al. National point prevalence of Clostridium difficile in US health care facility inpatients, 2008. Am J Infect Control. 2009;37:263-270. Gelone S. Clostridium difficile-associated disease: results of an international web-based surveillance project. Late breaking abstract. 16th Annual Meeting of the Society for Healthcare Epidemiology of America (SHEA). March 18-21, 2006; Chicago, IL. Gerding, D. N. 2007. New definitions will help, but cultures are critical for resolving unanswered questions about Clostridium difficile. Infection Control and Hospital Epidemiology. february 2007;28:113-115. Paul D. Stamper, et al. Comparison of a commercial real-time PCR assay for tcdB detection to a cell culture cytotoxicity assay and toxigenic culture for direct detection of toxin-producing Clostridium difficile in Clinical Samples. Journal of Clinical Microbiology. 2009;47:373-378. Ticehurst JR, et al. Effective Detection of Toxigenic Clostridium difficile by a Two-Step Algorithm Including Tests for Antigen and Cytotoxin. Journal of Clinical Microbiology. 2006;44:1145-1149. Sloan, L.M. et al. Comparison of Real-Time PCR for Detection of the tcdC Gene with Four Toxin Immunoassays and Culture in Diagnosis of Clostridium difficile Infection. JCM. 2008;46:1996-2001.

2.

3.

4.

5.

6.

Chlorhexidine-Impregnated Sponges Reduce Catheter-related Infections
ABSTRACT & COMMENTARY

By Robert Muder, MD
Hospital Epidemiologist, Pittsburgh VA Medical Center
Dr. Muder does research for Aventis and Pharmacia.

Synopsis: In a randomized, multicenter trial, chlorhexidine-impregnated sponges used in the dressing
June 2009

Similar Documents

Free Essay

Sociology and Nursing

...Gowning by attendants and visitors in newborn nurseries for prevention of neonatal morbidity and mortality Webster J, Pritchard MA Background - Methods - Results - Characteristics of Included Studies - References - Data Tables and Graphs [pic] Dates Date edited: 19/05/2006 Date of last substantive update: 31/01/2003 Date of last minor update: 05/04/2006 Date next stage expected 31/05/2006 Protocol first published: Issue 2, 2002 Review first published: Issue 3, 2003 Contact reviewer Joan Webster Nursing Director, Research Teaching and Research Royal Brisbane and Royal Women's Hospital and Health Service Districts Level 6, Ned Hanlon Building Butterfield Street Herston QLD AUSTRALIA 4029 Telephone 1: +61 7 3636 8590 Telephone 2: +61 7 3636 3140 Facsimile: +61 7 3636 2123 E-mail: joan_webster@health.qld.gov.au Contribution of reviewers Internal sources of support None External sources of support Centre for Clinical Studies - Women's and Children's Health, Mater Hospital, Sth Brisbane, Queensland, AUSTRALIA Department of Health and Ageing, Commonwealth Government, Canberra ACT, AUSTRALIA What's new This review updates the existing review of "Gowning by attendants and visitors in newborn nurseries for prevention of neonatal morbidity and mortality" which was published in The Cochrane Library Issue 2, 2003 (Webster 2003). No new trials were identified as a result of this updated search. The conclusions of the review are...

Words: 6846 - Pages: 28

Free Essay

Patient Safety Policy Paper

...Patient Safety Policy Paper Metropolitan State University NURS-605-50 Spring 2012 Introduction Patient safety is a primary goal for all health care workers, especially Registered Nurses who are the primary care givers for many patients. To promote safety and well-being it is important to provide the best possible care to all patients without spreading hospital acquired infections to patients that were previously free from certain diseases. Clostridium difficile infections (CDI) are a common occurrence within health care settings and can cause many complications, increasing length of stay, and could even cause death. The goal of this paper is to provide a policy to make changes to the Intensive Care Unit (ICU) at Mercy Hospital in Coon Rapids, Minnesota. The ICU has struggled with preventing and eliminating the spread of CDI from patient to patient. The unit has implemented many changes to increase hand hygiene, improve cleaning techniques of equipment, and increase staff knowledge and awareness without improvement of the CDI rates. By reviewing policies provided by the Agency for Healthcare Research and Quality (AHRQ) there can be changes made to improve the CDI rates at Mercy Hospital. Policy changes can be implemented and staff can be educated on proper hygiene techniques and other policies that the AHRQ will provide. The ultimate goal is to eliminate hospital acquired CDI’s and with the policy changes this can be a possibility. Policy Implementation ...

Words: 1330 - Pages: 6

Premium Essay

Clostridium Difficile

...| | | | | Clostridium Difficile | Clostridium Difficile The healthcare professional can expect to encounter various conditions within their scope of experience. Clostridium difficile represents one of the most common and challenging nosocomial infections that can cause life-threatening complications such as hypervolemia, sepsis, pain, and peritonitis (Grossman and Mager 155). The recognition, diagnosis, treatment and inhibition of transmission of this bacterium are imperative in order to limit infection and prevent death. “Clostridium difficile is a gram positive, spore forming anaerobic bacillus, which may or may not carry the genes for toxin A-B production” (Patel 102). In the 1930’s, Hall and O’Toole first identified C. difficile as plentiful normal bacterial flora in the feces of healthy infants. Initially, it was not considered a pathogen. However, by 1978, researchers recognized that toxins released by Clostridium were found in the fecal matter of patients with antibiotic associated diarrhea and concluded it as the cause of the infection (Keske and Letizia 329). The fecal-to-oral bacterial route transmits this particular bacterium. The ability of C. difficile to develop spores, enable this organism to persevere in the most extreme environmental settings. The spores can survive on common surfaces for months, including bedding, toilets and skin. The resistant quality of this bacterium increases its transmission and reinoculation rate...

Words: 1059 - Pages: 5

Free Essay

Microbiology in the News

...Microbiology and Infection Control Adrian Loadholt 1/15/2015 Dr. Momeny The article I read was entitled ‘putting it into practice: Infection control professionals’ perspective on early career nursing graduates’ microbiology and infection control knowledge and practice. Healthcare associated infections are most common but preventable infections in hospital patients. Control and prevention of healthcare-associated infections is a major focus and challenge for healthcare institutions worldwide. The article was related to a study conducted in Australia. The study included all females, who qualified as registered nurses and had spent at least 5 years working as a registered nurse before commencing their current infection control practitioner role. Half of the nurses were aged 35–59 years and had completed their undergraduate training in the university setting, while the other half were hospital-trained nurses aged 40 years or older. All but one participant had taken training in infection control. All participants indicated that many new graduates had deficits in their infection control and associated microbiology knowledge, with some describing graduates’ level of infection control knowledge as ‘very poor’ or ‘basic’. One of the participants thought that the new graduates’ would lose knowledge after a period of time in the workplace. The participants agreed that increasing the amount of microbiology in the curriculum would improve graduates’ understanding and implementation...

Words: 351 - Pages: 2

Free Essay

Vidas Menu

...Assay Solution P ION EER I NG DIAGNOSTICS EMERGENCY (1) BACTERIAL INFECTION B.R.A.H.M.S PCT™ (Procalcitonin) CARDIAC 10-14 / 9308596/008/GB/R bioMérieux, the blue logo and VIDAS are used, pending and/or registered trademarks belonging to bioMérieux, or one of its subsidiaries, or one of its companies. Any other name or trademark is the property of its respective owner. bioMérieux SA RCS Lyon 673 620 399 Photos C.Ganet, N.Bouchut / Printed in France / théra / RCS Lyon B 398 160 242 NT-proBNP2 Troponin I Ultra hs Troponin I* Galectin-3 Myoglobin CK-MB Digoxin Ref 1 30450 Kit size 60 tests 30458 30448 415386 411191 30446 30421 30603 myQC 60 tests 60 tests 60 tests 60 tests 30 tests 30 tests 60 tests VENOUS THROMBOEMBOLISM / COAGULATION D-Dimer Exclusion IITM Protein C vWF 30455 30115 30436 60 tests 30 tests 30 tests INFECTIOUS DISEASES (1) HEPATITIS HAV IgM .......................................................... Anti-HAV Total ............................................. HBs Ag Ultra .................................................. HBs Ag Ultra Confirmation....................... Anti-HBs Total Quick................................. Anti-HBs Total II** ..................................... Anti-HBc Total II .......................................... HBc IgM II ....................................................... HBe-Anti HBe................................................ Anti-HCV.....

Words: 672 - Pages: 3

Premium Essay

Isolation

...Patients receiving chemotherapy treatments are a vulnerable population. They are susceptible to many infections and transmittable diseases, due to the suppression of their immune system by cytotoxic medications. The susceptible patients are usually merged within the population of hospital and clinical treatment centers, where their exposure to infections is likely (Siegel, Rhinehart, Jackson, Chiarello, & the Healthcare Infection Control Practices Advisory Committee, 2007). In the outpatient clinical setting, a cancer patient is scheduled to come in and receive his/her chemotherapy treatments, as well as visit with his/her oncology physician. Once the treatments are completed, he/she may then leave. This arrangement is enticing for both the patient, and the hospital. The patient is not confined to the hospital for the length of his/her treatment, and the hospital can reduce their patient load, thus having the ability to focus on those who are in need of critical care. The outpatient clinic, however, is not without risk. The ever-plastic environment, as well as the, “various interactions and contacts of patients at different institutions of care” (Vaartico-Rajalin et al., 2015, p. 2) can expose them, their families, and caregivers to the many lurking infections that are not as easily controlled. Infections transmitted in this manner are termed hospital acquired infections (HAI). To protect everyone in these environments, as well as in any care institution or home care setting from...

Words: 582 - Pages: 3

Premium Essay

The Negative Effects Of Pooof Pills

...Although the term poop pills may sound disgusting, it may just be a life changing antibiotic. Thousands of Americans get Clostridium difficile (C-diff) each year and 14,000 of them die from C-diff. But, there is an antibiotic that’s known to destroy the C-diff and also harm the body as well. Though studies show that a fecal transplant can restore the bacteria and prevent infections to form in your body. Doctors have gave the transplant a try, but they have not really been successful. The stool that is transplanted usually comes from relatives, and doctors extract the bacteria from the poop and insert it into gel capsules. Even though this pill seems gross, the pill does not affect the smell or health of your body. This transplant does require...

Words: 271 - Pages: 2

Free Essay

Annotated Bibliography

...A. R. K Baker ENG 102 4 May 2012 Microorganisms at Work This topic is about how microorganisms continue to live in hospital rooms even after the rooms have been cleaned. The organisms that concern me are the multi resistant ones. It starts with a patient who is in isolation because of one of these bacteria’s and then discharged from the hospital after they are well. If these organisms are on the bedside table or the handrails the patient is already cured so it will not affect them. What about the patient coming in the room next? It is left to the housekeepers to clean the room well enough to prevent the spread of these infections. These infections that are spread from one patient to another are called nosocomial infections. They are hospital acquired bacteria’s. I came to this topic after my daughter had this exact thing happen to her. She is a brittle diabetic and at one point required a lot of hospital visits. After one of these visits she started to develop a boil. This in turn caused her blood sugar to go up and we ended up back in the hospital. Thinking the boil was a spider bite we were surprised to find out it was methicillin-resistant Staphylococcus aureus (MRSA). They explained that it was a nosocomial infection that was probably acquired on our last hospital visit. When asked how she got it they said it was multi resistant and was passed from something she came in contact with that another patient would have touched. This is a problem that has been on the...

Words: 1505 - Pages: 7

Premium Essay

Clostridium Difficlie

...Clostridium Difficlie Amy Roger Margaret Mcgannon Learning about Clostridium difficile Clostridium difficile also known a C. difficile or C. diff is an inflammatory infection created in the intestine primarily caused by taking antibiotics. Most people don’t show symptoms of having the C. diff bacteria in your intestines until that person has taken a course of antibiotics. Clostridium difficile bacteria can be found anywhere in the environment. It is found is soil, water, human and animal feces, food products and processed meats (Mayo clinic staff, 2013). Treatments to cure C. diff include antibiotics and surgery. Once having C. diff you want to make sure that you can prevent from getting it again. The best way to prevent from getting C. diff for the first time or a recurring time is to simply wash your hands, avoid unsanitary environments, disinfect surfaces that could possibly be infected, and try to avoid antibiotics when possible (Mayo clinic staff, 2013). Every person has bacteria already in their intestines that help to fight off illness and other bad bacteria that are introduced into the body. When a person takes antibiotics it not only kills that bad bacteria but also kills the good bacteria as well. If a person has Clostridium difficile bacteria in their system it allows the bacteria to grow and causes inflammation in the intestines. Once someone has the Clostridium difficile bacteria in their body and taking antibiotics it allows them to grow out of control causing...

Words: 790 - Pages: 4

Premium Essay

Antibiotic Misuse

...There are several people who use antibiotics for the wrong reasons. Some people think that using antibiotics will get rid of a cold or the flu virus faster or clear up a skin condition. Antibiotics should only be consumed for the infectious illness in which they were suggested for. Antibiotics are abused world-wide, and abuse of the medication can do more harm than help. I chose to research antibiotic abuse and the underlying issues with antibiotics. Antibiotics are being abused in so many ways by people and industries everywhere. The focus will be on agricultural abuse of antibiotics, human abuse, and antibiotic resistance. I will conduct various phone or face to face interviews with individuals as well as provide a questionnaire survey to obtain the information needed for this particular project. What are antibiotics? Antibiotics are “A medicine (such as penicillin or its derivatives) that inhibits the growth of or destroys microorganisms”, (What You Should Know about Antibiotics, 2012, p. 3). Antibiotics are used to treat various infections within the body cavity. They help ward off unwanted illnesses. There are various types of antibiotics each one has a significant role in fighting bacteria or fungal infections. “How do antibiotics work? When properly prescribed for a bacterial illness, antibiotics join forces with your body’s own defenses and literally wage war against invading bacteria. Some antibiotics dissolve the protective cell wall of an organism, rupturing and...

Words: 1681 - Pages: 7

Free Essay

C Diff

...Clostridium Difficlie (C diff) Clostridium Difficlie, also known as C diff, is a bacterium infection that has symptoms of diarrhea but can also have life threatening inflammation of the colon (staff, 2012). C. diff most commonly affects older adults primarily those that are hospitalized or in a long term care setting (staff, 2012). “An epidemic of Clostridium difficle in the United States is now killing some 12,000 patients annually, in part because neither alcohol rubs nor soap and water used in the vast majority of hospitals can effectively remove the spore-forming bacillus from the hands of health care workers, researchers are finding” (Hand hygiene woes impact C.diff response, 2010,pg 76).Let’s explore Clostridium difficle a little, how it is transmitted, the environmental factors, standard treatments and ways to help prevent the spread of Clostridium Difficlie. Clostridium Difficlie bacteria are passed in feces and thru food, they are also on surfaces or objects where people fail to wash their hands when they are infected. These bacteria spores can last in a room for weeks or even months so if you touch an infected surface you can unknowingly ingest the bacteria (staff, 2012). Normally healthy people don’t get sick from the bacteria because your body contains many types of bacteria that will fight off the infection. However, many people get C. diff following a treatment with antibiotics. “The antibiotics that most often lead to C. difficle infections include fluoroquinolones...

Words: 856 - Pages: 4

Free Essay

Wrqwataq

...Clostridium difficile, also known as "CDF/cdf", or "C. diff", is a species of Gram-positive bacteria of the genus Clostridium that causes severe diarrhea and other intestinal disease when competing bacteria in the gut flora have been wiped out by antibiotics. Clostridia are anaerobic, spore-forming rods. C. difficile is the most serious cause of antibiotic-associated diarrhea (AAD) and can lead to pseudomembranous colitis, a severe inflammation of the colon, often resulting from eradication of the normal gut flora by antibiotics. In a very small percentage of the adult population, C. difficile bacteria naturally reside in the gut. Other people accidentally ingest spores of the bacteria while they are patients in a hospital, nursing home, or similar facility. When the bacteria are in a colon in which the normal gut flora has been destroyed (usually after a broad-spectrum antibiotic such as clindamycin has been used), the gut becomes overrun with C. difficile. This overpopulation is harmful because the bacteria release toxins that can cause bloating and diarrhea, with abdominal pain, which may become severe. C. difficile infections are the most common cause of pseudomembranous colitis, and in rare cases this can progress to toxic megacolon, which can be life-threatening. Latent symptoms of C. difficile infection often mimic some flu-like symptoms and can mimic disease flare in patients with inflammatory bowel disease-associated colitis.[4] Mild cases of C. difficile infection...

Words: 2925 - Pages: 12

Premium Essay

Clostridium Difficile

...Running head: CLOSTRIDIUM DIFFICILE Clostridium difficile Jane Doe A University   Clostridium difficile Pathophysiology Clostridium difficile is a gram positive, spore forming anaerobic bacillus, which may or may not carry the genes for toxin A-B production (Nipa, 2010). These two types of protein exotoxins produced by the Clostridium difficile bacillus, toxin A and toxin B, can have an infectious form and a non-active, non-infectious form (Grossman, 2010). The infectious form can survive for a short duration of time in the environment. The spores can survive for a longer period of time in the environment and are not infectious unless and until they are ingested or are transformed into an infectious state (Nipa, 2010). Together, the two toxins cause a large number of inflammatory mediators to descend on the colon, triggering more colitis and colonic ulcerations. Purulent debris then results, contributing to the development of a pseudomembrane. With the activation of the inflammatory response, the released mediators cause fluid secretion and increased permeability at the mucosal membrane and predispose the patient to diarrhea as well as drastic electrolyte and fluid shifts (Grossman, 2010). Signs and Symptoms Symptoms caused by infection with Clostridium difficile range from mild diarrhea to profuse, watery diarrhea accompanied by severe inflammation of the intestine (Gould, 2010). Patient may complain of foul smelling diarrhea (Grossman, 2010). Symptoms may also...

Words: 811 - Pages: 4

Premium Essay

Clostridium Difficle

...Clostridium difficile (klos-TRID-e-um dif-uh-SEEL), often called C. difficile or C. diff, is a bacterium that can cause symptoms ranging from diarrhea to life-threatening inflammation of the colon. Illness from C. difficile most commonly affects older adults in hospitals or in long-term care facilities and typically occurs after use of antibiotic medications. However, studies show increasing rates of C. difficile infection among people traditionally not considered high risk, such as younger and healthy individuals without a history of antibiotic use or exposure to health care facilities. Each year, more than a half million people get sick from C. difficile, and in recent years, C. difficile infections have become more frequent, severe and difficult to treat. Some people carry the bacterium C. difficile in their intestines but never become sick, though they can still spread the infection. C. difficile illness usually develops during or within a few months after a course of antibiotics. Clostridium difficile is shed in feces. Any surface, device, or material (e.g., toilets, bathing tubs, and electronic rectal thermometers) that becomes contaminated with feces may serve as a reservoir for the Clostridium difficile spores. Clostridium difficile spores are transferred to patients mainly via the hands of healthcare personnel who have touched a contaminated surface or item. Clostridium difficile can live for long periods on surfaces.Whenever possible, other antibiotics should...

Words: 446 - Pages: 2

Free Essay

Nosocomial Infections

...Nosocomial Infections Monica Butler Strayer University Dr. Godson Ezejiofo HSA 535 Managerial Epidemiology January 25, 2015 Introduction Good Health Hospital has proved to be among the best hospitals in the region since its inception. The medical professionals and all members of staff are always committed to ensuring delivery of quality services to patients. The hospital has had a good reputation of excellent staff, good patient relations and top quality services. In the recent past, several cases of E. coli have been reported at Good Health Hospital. E. coli exists in a variety of types but most varieties a less harmful to human health. Research by medical professionals has shown that E. coli bacteria live in the intestines, for both people and animals. Symptoms of E. coli infection include diarrhea, abdominal pain and vomiting (Bennett, Jarvis & Brachman, 2007). E. coli emanates from taking contaminated food and water. E. coli may lead to death or permanent health problems if appropriate measures are taken on time. Nosocomial diseases can be termed as an infection that a person gets while being attend to in a health institution. The goal for this task is to explore the nosocomial infections, intervention strategies and recommendations on how to control and manage the various types of nosocomial infections. Analysis of Good Health Hospital records Records of Good Health Hospital show that a number of nosocomial diseases have been reported. Among the commonest...

Words: 1331 - Pages: 6