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Path of Digestive System

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I ate a ham and swiss cheese sandwich for lunch on Day Three, which contained all three macronutrients. There was carbohydrate from the Asiago cheese bread, fat from the swiss cheese, and protein from the ham. Digestion of this sandwich began in my mouth, when I bit into it and chewed the macronutrients into smaller pieces with my teeth. Then the saliva, secreted from the salivary glands, moistened the food and began the chemical breakdown of the food. Amylase, an enzyme in the saliva, broke down the complex carbohydrates. Once the food was chewed in my mouth, the trachea closed and the upper esophageal sphincter, a muscle at the top of the esophagus, opened to allow passage of food into the esophagus. Then the food moved from the esophagus to the stomach by gravity and the rhythmic pulsing of inner and outer muscles of the esophagus, called peristalsis. Once the food reached the end of the esophagus, the gastroesophageal sphincter relaxed and the food passed into the stomach. As soon as the food reached the stomach, it was mixed with the gastric juice that contains important compounds used to further digest the protein and fats. This is known as the gastric phase, when the hormone gastrin was secreted. Gastrin stimulated stomach contractions, which mixed and churned the food until it became chyme. Gastrin also increased the secretion of the gastric cells, which made the gastric juices more acidic. The gastric juice contains hydrochloric acid, gastric lipase, and mucus. The hydrochloric acid (HCl) denatured the proteins by uncoiling the bonds. The HCl also converted pepsinogen into pepsin, which digested proteins into smaller components. Gastric lipase, an enzyme, began the fat (lipid) digestion. The mucus in the gastric juice protected the stomach from the acidity from the HCl and pepsin. The stomach lining also began to absorb substances such as water, medium-chain

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