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Plasmodium Falciparum

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Submitted By mmcgriff2163
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Plasmodium falciparum is a protozoan parasite. It is unique of the class of Plasmodium that is the foundation and cause malaria in individuals. There are other Plasmodium species that can cause malaria in humans. Nevertheless P. falciparum is the most common, virulent, and deadly. P. falciparum communicable by the female Anopheles mosquito.
P. falciparum life cycle is comprised of two hosts. A P. falciparum carrier female Anopheles mosquito injects sporozoites into the human, infecting their liver cells. Once there infection and damage to red blood cells is critical to the parasites survival. Because red blood cells transport oxygen all over the body, their destruction by P. falciparum causes basic functional devastation to the host. Plasmodium falciparum increase the speed glucose synthesis in red blood cells causing a large yield of energy. P. falciparum use a hefty portion of this energy to destroy hemoglobin proteins in the cells and to inhibit damaging chemical reactions related to the breakdown. During the destruction of the red blood cells P. falciparum treat the amino acids as waste and are usually discarded from the cell, instead of being used to make their own protein from the hemoglobin breakdown.
The sporozoites developed into schizonts, which lyse and discharge merozoites into the blood streem. This is termed exo-erythrocytic schizogony. Once that happens, the parasites go through asexual duplication in the erythrocytes, called erythrocytic schizogony. The merozoites infect red blood cells. During ring stage of P. falciparum infection cycle, red blood cells remain their standard in size and do not enlarge. Normally merely rings and gametocytes are able to be seen under a microscope. P. falciparum rings have faint cytoplasm with one or two chromatin dots, creating the classic headphones appearance. Usually the parasite infects some of the same red...

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