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Esophagus Essay

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Introduction
The esophagus is a muscular tube connecting the throat with the stomach, its about 8 inches long. The primary function of the esophagus is to transfer food from the mouth to the stomach. The food is transported in rhythmic wave contractions of the muscles, a technique called peristalsis. The esophagus is layered by three types of tissue mucosa, sub-mucosa and muscularis externa. The mucosa consists of cells such as fibroblasts, fibrocycts, vascular endothelial and smooth muscle cells. Since this layer is the innermost layer directly in contact with food, the layer facilitates frictionless passage of food bolus by constantly lubricating the surface with grandular secretions. Followed by the mucosa layer is the sub-mucosa layer that …show more content…
"Bioartificial oesophagus in the era of tissue engineering." Journal of pediatric gastroenterology and nutrition 52 (2011): S16-S17.
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 Saxena, Amulya K., et al. "Esophagus tissue engineering: in situ generation of rudimentary tubular vascularized esophageal conduit using the ovine model."Journal of pediatric surgery 45.5 (2010): 859-864.
 Tan, Bo, et al. "Tissue engineered esophagus by mesenchymal stem cell seeding for esophageal repair in a canine model." Journal of Surgical Research182.1 (2013): 40-48.
 Chen, Mei-Chin, et al. "A novel drug-eluting stent spray-coated with multi-layers of collagen and sirolimus." Journal of controlled release 108.1 (2005): 178-189.
 Miki, Hirotaka, et al. "An artificial esophagus constructed of cultured human esophageal epithelial cells, fibroblasts, polyglycolic acid mesh, and collagen."ASAIO journal 45.5 (1999): 502-508.
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